Santu Mofokeng was born in Johannesburg in 1956, and began his career as a street photographer in Soweto during the apartheid era.

For ten years he held the position of researcher and documentary photographer in the Institute for Advanced Social Research (formerly African Studies Institute) at the University of the Witwatersrand. A freelance curator, writer, researcher and photographer, Mofokeng produces work concerned with issues of representation. His photography has been featured in major exhibitions around the world, for example his "Rethinking Landscapes" presented at the Fifth International African Photography Festival in Bamako, Mali in 2003, and in Paris, France the following year. He has also had exhibitions in China, Belgium, Germany, Japan, the Netherlands, Spain, and the United States. He is based in Johannesburg, South Africa.

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